of Physical Chemistry of
Transformation of Polymers
of the Laboratory: Professor Arkady P. Sinitsyn
Department of Chemistry, M.V.Lomonosov
Moscow State University,
Moscow 119899, Russia
939-5966 Fax: (7-495)
The laboratory was founded in 1991, when Cellulase Research
Group at the Division of Chemical Enzymology, M.V.Lomonosov Moscow State
University, received the status of laboratory. From the moment of establishment
of the Division of Chemical Enzymology in 1974 by Professor Ilya Berezin,
Cellulase Research Group was led by Dr. Anatole Klyosov. Since 1982, Dr.
Arkady Sinitsyn has been the head of the Cellulase Research Group.
The major research directions of the laboratory are as follows:
Enzymology, biochemistry and biotechnology
of enzymes catalyzing the biodegradation of polysaccharides:
purification and investigation of properties of
purified individual enzymes;
development of methods for determination of enzymatic
kinetics of multienzyme systems participating
in the hydrolysis of polysaccharides;
study of enzyme adsorption and mechanisms of soluble
and insoluble polysaccharide biodegradation;
investigation of the role of transglycosylation
in hydrolysis of poly- and oligosaccharides by carbohydrases.
Screening, selection, mutagenesis and development of active
microbial strains - producers of acid, neutral and alkaline carbohydrases
(in cooperation with Institute of Biochemistry and Physiology of Microorganisms,
Russian Academy of Sciences):
screening and finding of wild strains;
mutagenesis and development of strains - superproducers
of the target enzyme;
optimization of fermentation processes, their
scaling up and commercialization.
Enzyme applications in food, textile,
pulp and paper industry and as feed additives:
development of laboratory micro- and express-methods
modeling the enzyme behavior under real conditions;
enzyme application trials.
publications of the laboratory includes 4 books and more than 200 papers
in international and national journals.
You may contact the laboratory using E-mail:
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